Hormone replacement therapy is the medical treatment system for the surgical postmenopausal, premenopausal and menopausal women and the transgender men. It is basically based on idea which the treatment can avoid the discomfort caused due to the diminishing circulating progesterone hormones and estrogens. In case of premature or even surgical menopausal, that usually continue through a person’s life and reduces the chances of having dreadful diseases like dementia. The hormone replacement therapy involves more than one medication groups designed for artificially boosting the level of hormones. The main hormone types that are involved are progestin, progesterone or estrogens and sometimes testosterone are also involved. It is more of a treatment for hormones rather than a therapy. The hormone therapy is also routinely used for the treatment of the menopausal symptoms and to protect the long-term health.